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Submit ReviewFPL 55712
Discontinued Product
2276 has been discontinued.
View all Leukotriene and Related Receptors products.
说明： Leukotriene receptor antagonist
化学名： 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid
纯度： ≥97% (HPLC)
生物活性 for FPL 55712
FPL 55712 is a leukotriene receptor antagonist; inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4.
技术数据 for FPL 55712
| 分子量 | 498.52 |
| 公式 | C27H30O9 |
| 储存 | Store at -20°C |
| 纯度 | ≥97% (HPLC) |
| CAS Number | 40785-97-5 |
| PubChem ID | 105007 |
| InChI Key | LMQBMWHHGVZWMR-UHFFFAOYSA-N |
| Smiles | CCCC1=C(O)C(=CC=C1OCC(O)COC1=CC=C2C(=O)C=C(OC2=C1CCC)C(O)=O)C(C)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for FPL 55712
参考文献 for FPL 55712
参考文献是支持产品生物活性的出版物。
Jones et al (1983) Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachealis: interaction with FPL-55712. Prostaglandins 26 833 PMID: 6322240
O'Donnell and Welto (1984) Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions 14 43 PMID: 6322547
Folkerts et al (1995) Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur.J.Pharmacol. 285 R1 PMID: 8566126
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关键词: FPL 55712, FPL 55712 supplier, leukotrienes, eicosanoids, receptor, antagonists, CysLT1, Receptors, receptors, LTD4, LTE4, FPL55712, Leukotriene, and, Related, 2276, Tocris Bioscience
1 篇 FPL 55712 的引用文献
引用文献是使用了 Tocris 产品的出版物。 FPL 55712 的部分引用包括：
Wright et al (2019) Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2. Biochem Biophys Res Commun 520 35 PMID: 31564414
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