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Submit ReviewFuranone C-30 is a synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing in vivo and promotes bacterial clearance in a mouse pulmonary infection model.
分子量 | 253.88 |
公式 | C5H2Br2O2 |
储存 | Store at -20°C |
纯度 | ≥98% |
CAS Number | 247167-54-0 |
PubChem ID | 67228456 |
InChI Key | DPGLBHQUHFJRJS-UHFFFAOYSA-N |
Smiles | Br/C=C1OC(C=C\1Br)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Hentzer et al (2003) Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22 3803 PMID: 12881415
关键词: Furanone C-30, Furanone C-30 supplier, quorum, sensing, sensors, Gram-negative, signaling, signalling, inhibits, inhibitors, antibacterial, Antibiotics, 6546, Tocris Bioscience
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