G10

Name: G10
Brand: Tocris Bioscience
SKU: 5944

Cat. No. 5944 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5944 has been discontinued.

View all STING-Dependent Signaling products.

说明： Activator of STING-dependent signaling

化学名： 4-[(2-Chloro-6-fluorophenyl)methyl]-N-(2-furanylmethyl)-3,4-dihydro-3-oxo-2H-1,4-benzothiazine-6-carboxamide

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for G10

G10 is an activator of STING-dependent signaling; exhibits no direct binding affinity for STING. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. Exhibits no effect on NF-κB signaling. Blocks viral replication in vitro.

化合物库 for G10

G10 is also offered as part of the Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。

技术数据 for G10

分子量	430.88
公式	C₂₁H₁₆ClFN₂O₃S
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	702662-50-8
PubChem ID	5077622
InChI Key	NAGKYJATVFXZKN-UHFFFAOYSA-N
Smiles	FC1=CC=CC(Cl)=C1CN2C(CSC3=CC=C(C(NCC4=CC=CO4)=O)C=C23)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for G10

分析证书/产品说明书

化学品安全技术说明书

参考文献 for G10

参考文献是支持产品生物活性的出版物。

Sali et al (2015) Characterization of a novel human-specific STING agonist that elicits antiviral activity against emerging alphaviruses. PLoS Pathog. 11 e1005324 PMID: 26646986

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关键词: G10, G10 supplier, STING-dependent, signaling, activators, activates, interferons, IRF3, antiviral, STING-Dependent, Signaling, 5944, Tocris Bioscience

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G10