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Submit ReviewN-terminal galanin fragment. In contrast to the full length (1-29) peptide, mediates central cardiovascular effects, perhaps by binding to a novel receptor type.
分子量 | 1556.74 |
公式 | C72H105N19O20 |
序列 | GWTLNSAGYLLGPHA |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 112747-70-3 |
PubChem ID | 16131409 |
InChI Key | LOXLDVDBPRBBLT-GDRYISODSA-N |
Smiles | [H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Amiranoff et al (1989) Structural requirements for galanin action in the pancreatic β cell line rin m 5F. Eur.J.Pharmacol. 163 205 PMID: 2472967
Narvaez et al (2000) The galanin receptor antagonist M40 blocks the central cardiovascular actions of the galanin N-terminal fragment (1-15). Eur.J.Pharmacol. 399 197 PMID: 10884520
Xu et al (1999) Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons. Proc.Natl.Acad.Sci.USA 96 14583 PMID: 10588748
关键词: Galanin (1-15) (porcine, rat), Galanin (1-15) (porcine, rat) supplier, Galanin, receptor, agonists, peptide, GAL, GalR, Receptors, 1450, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Galanin (1-15) (porcine, rat) 的部分引用包括:
Stratford et al (2017) Immunocytochemical organization and sour taste activation in the rostral nucleus of the solitary tract of mice. J Comp Neurol 525 271 PMID: 27292295
Millòn et al (2014) A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats. Int.J.Neuropsychopharmacol. 18 PMID: 25522404
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.