Galanin (1-29) (rat, mouse)

Cat. No. 2696 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Non-selective galanin receptor agonist

纯度： ≥95% (HPLC)

引用文献 (5)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Galanin (1-29) (rat, mouse)

Galanin (1-29) (rat, mouse) is a non-selective galanin receptor agonist (K_i values are 0.98, 1.48 and 1.47 nM for GAL₁, GAL₂ and GAL₃ respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.

技术数据 for Galanin (1-29) (rat, mouse)

分子量	3164.48
公式	C₁₄₁H₂₁₁N₄₃O₄₁
序列	GWTLNSAGYLLGPHAIDNHRSFSDKHGLT (Modification: Thr-29 = C-terminal amide)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	114547-31-8
PubChem ID	16201477
InChI Key	JHQDYHHNJBOXKP-UPNHMZDKSA-N
Smiles	[H]NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Galanin (1-29) (rat, mouse)

溶解性	Soluble to 1 mg/ml in water

产品说明书 for Galanin (1-29) (rat, mouse)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Galanin (1-29) (rat, mouse)

参考文献是支持产品生物活性的出版物。

Wang et al (1997) Cloning and expression characterization of a novel galanin receptor. J.Biol.Chem. 272 51 PMID: 8995226

Mazarati et al (2006) Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: the effects of subtype-selective agonists and the role of G-protein-mediated signaling. J.Pharmacol.Exp.Ther. 318 700 PMID: 16699066

Branchek et al (2000) Galanin receptor subtypes. TiPS. 21 109

If you know of a relevant reference for Galanin (1-29) (rat, mouse), please let us know.

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关键词: Galanin (1-29) (rat, mouse), Galanin (1-29) (rat, mouse) supplier, Non-Selective, galanin, receptors, agonists, GAL, GalR, Galanin, Receptors, 2696, Tocris Bioscience

5 篇 Galanin (1-29) (rat, mouse) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Galanin (1-29) (rat, mouse) 的部分引用包括：

Li (2017) Involvement of galanin and galanin receptor 1 in nociceptive modulation in the central nucleus of amygdala in normal and neuropathic rats. Sci Rep 7 15317 PMID: 29127424

Zhang (2017) Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulatecortex of normal rats and rats with mononeuropathy. Sci Rep 7 45930 PMID: 28378856

Einstein et al (2013) Galanin-induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and mor. conditioned place preference require both galanin receptor 1 and galanin receptor 2. Eur J Neurosci 37 1541 PMID: 23387435

Funck (2018) Dorsal hippocampal galanin modulates anxiety-like behaviours in rats. Brain Res 1687 74 PMID: 29499176

Gey et al (2016) Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol 6 PMID: 27581653

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