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Submit ReviewGP 2a
说明： Selective CB2 agonist
化学名： N-Cyclohexyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide
纯度： ≥99% (HPLC)
生物活性 for GP 2a
GP 2a is a selective CB2 receptor agonist; Ki values are 7.6 and 900 nM for CB2 and CB1 receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.
技术数据 for GP 2a
| 分子量 | 440.36 |
| 公式 | C24H23Cl2N3O |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 919077-81-9 |
| PubChem ID | 16094766 |
| InChI Key | SPEFJYZGXZENAF-UHFFFAOYSA-N |
| Smiles | CC1=CC=C2C(CC3=C2N(N=C3C(=O)NC2CCCCC2)C2=CC=C(Cl)C=C2Cl)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for GP 2a
参考文献 for GP 2a
参考文献是支持产品生物活性的出版物。
Murineddu et al (2006) Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxam J.Med.Chem. 49 7502 PMID: 17149879
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关键词: GP 2a, GP 2a supplier, Selective, CB2, agonists, cannabinoids, Receptors, GP2a, cb2r, 2678, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.