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说明： Selective partial FFA4 (GPR120) agonist
化学名： 2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-benzoic acid
纯度： ≥98% (HPLC)
生物活性 for Grifolic acid
Grifolic acid is a selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.
技术数据 for Grifolic acid
| 分子量 | 372.5 |
| 公式 | C23H32O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 80557-12-6 |
| PubChem ID | 9976563 |
| InChI Key | QPIZDZGIXDKCRC-JTCWOHKRSA-N |
| Smiles | OC1=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)C(O)=C(C(O)=O)C(C)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Grifolic acid
参考文献 for Grifolic acid
参考文献是支持产品生物活性的出版物。
Hara et al (2009) Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch.Pharmacol. 380 247 PMID: 19471906
Sun et al (2010) Structure-activity relationships of GPR120 agonists based on a docking simulation. Mol.Pharmacol. 78 804 PMID: 20685848
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关键词: Grifolic acid, Grifolic acid supplier, G, protein-coupled, receptors, GPR120, orphan, selective, partial, agonists, FFA4, free, fatty, acid, Free, Fatty, Acid, Receptors, 4581, Tocris Bioscience
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