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Submit ReviewGuanylin (human)
说明： Endogenous activator of intestinal guanylyl cyclase
纯度： ≥95% (HPLC)
生物活性 for Guanylin (human)
Guanylin (human) is an endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.
技术数据 for Guanylin (human)
| 分子量 | 1458.65 |
| 公式 | C58H87N15O21S4 |
| 序列 |
PGTCEICAYAACTGC (Modifications: Disulfide Bridges: 4-12, 7-15) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 183200-12-6 |
| PubChem ID | 90488722 |
| InChI Key | XPNQMTAYRNMRRD-RDJGHUJSSA-N |
| Smiles | [H]N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC1=O)[C@@H](C)CC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Guanylin (human)
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for Guanylin (human)
参考文献 for Guanylin (human)
参考文献是支持产品生物活性的出版物。
Beltowski (2001) Guanylin and related peptides. J.Physiol.Pharmacol. 52 351 PMID: 11596856
Currie et al (1992) Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 89 947 PMID: 1346555
Nokihara et al (1997) Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 70 111 PMID: 9272623
If you know of a relevant reference for Guanylin (human), please let us know.
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关键词: Guanylin (human), Guanylin (human) supplier, Endogenous, activators, intestinal, guanylyl, cyclase, sGC, Guanylyl, cyclases, Cyclase, 1898, Tocris Bioscience
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