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Submit ReviewHexylHIBO
Discontinued Product
1749 has been discontinued.
View all Glutamate (Metabotropic) Group I Receptors products.
说明： Group I mGlu antagonist
别名： Hexylhomoibotenic acid
化学名： α-Amino-4-hexyl-2,3-dihydro-3-oxo-5-isoxazolepropanoic acid
纯度： ≥98% (HPLC)
生物活性 for HexylHIBO
HexylHIBO is a group I mGlu receptor antagonist (Ki values are 140 and 110 μM at mGlu1a and mGlu5a receptors respectively). Decreases sEPSCs in rat pyramidal neurons in vitro.
S-enantiomer also available.
技术数据 for HexylHIBO
| 分子量 | 256.3 |
| 公式 | C12H20N2O4 |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 334887-43-3 |
| PubChem ID | 3984764 |
| InChI Key | OKJBLHIYOWSQDJ-UHFFFAOYSA-N |
| Smiles | OC1=NOC(CC(C(O)=O)N)=C1CCCCCC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for HexylHIBO
化学品安全技术说明书目前不在网上提供。
请联系客户服务。
请联系客户服务。
参考文献 for HexylHIBO
参考文献是支持产品生物活性的出版物。
Bandrowski et al (2003) Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex. J.Neurophysiol. 89 1308 PMID: 12626613
Madsen et al (2001) Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors. J.Med.Chem. 44 1051 PMID: 11297452
关键词: HexylHIBO, HexylHIBO supplier, Group, I, mGlur, antagonists, Receptors, mGlu1, mGluR1, mGlu5, mGluR5, Glutamate, Metabotropic, Hexylhomoibotenic, acid, (Metabotropic), 1749, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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