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Submit Review(S)-HexylHIBO
Discontinued Product
1750 has been discontinued.
View all Glutamate (Metabotropic) Group I Receptors products.
Description: Group I mGlu antagonist
Alternative Names: (S)-Hexylhomoibotenic acid
Chemical Name: (αS)-α-Amino-4-hexyl-2,3-dihydro-3-oxo-5-isoxazolepropanoic acid
Purity: ≥99% (HPLC)
Biological Activity for (S)-HexylHIBO
Group I mGlu receptor antagonist (Kb values are 30 and 61 μM at mGlu1a and mGlu5a receptors respectively).
Racemate also available.
Technical Data for (S)-HexylHIBO
| M. Wt | 256.3 |
| Formula | C12H20N2O4 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 334887-48-8 |
| PubChem ID | 6604908 |
| InChI Key | OKJBLHIYOWSQDJ-VIFPVBQESA-N |
| Smiles | OC1=NOC(C[C@@H](C(O)=O)N)=C1CCCCCC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for (S)-HexylHIBO
References for (S)-HexylHIBO
References are publications that support the biological activity of the product.
Madsen et al (2001) Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors J.Med.Chem. 44 1051 PMID: 11297452
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Keywords: (S)-HexylHIBO, (S)-HexylHIBO supplier, Group, I, mGlur, antagonists, Receptors, mGlu1, mGluR1, mGlu5, mGluR5, Glutamate, Metabotropic, (S)-Hexylhomoibotenic, acid, (Metabotropic), 1750, Tocris Bioscience
Citations for (S)-HexylHIBO
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Currently there are no citations for (S)-HexylHIBO.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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