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Submit ReviewPotent antagonist of bombesin/gastrin releasing peptide.
Sold with the permission of AstraZeneca UK Ltd.
分子量 | 916.09 |
公式 | C45H65N13O8 |
序列 | HWAVAHL (Modications: His-1 = N-Isobutyryl, Ala-5 = D-Ala, Leu-7 = Leu-NHMe) |
储存 | Desiccate at -20°C |
CAS Number | 124001-41-8 |
Smiles | O=C(NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C(C)C)Cc1cncn1)Cc3c2ccccc2nc3)C)C(C)C)C)Cc4cncn4)[C@@H](NC)CC(C)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Camble et al (1989) N-Isobutyryl-His-Trp-Ala-Val-D-Ala-His-Leu-NHMe (ICI 216,140) a potent in vivo antagonist analog of bombesin/gastrin releasing peptide (BN/GRP) derived from the C-terminal sequence lacking the final methionine residue. Life Sci. 45 1521 PMID: 2555638
Camble et al (1989) ICI-216,140 and other potent in vivo antagonist analogs of bombesin/gastrin releasing peptide. Pept.Chem.,Struct.Biol.,Proc.Am.Pept.Symp.11th mee 174
关键词: ICI 216,140, ICI 216,140 supplier, Potent, Bombesin/Gastrin, releasing, peptide, antagonists, GRP-Preferring, Receptors, BB1BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, Bombesin, ICI216140, AstraZeneca, 0823, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.