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Submit ReviewIsamoltane hemifumarate is a 5-HT1B antagonist, approximately 30-fold selective over 5-HT1A. Also possesses affinity for β-adrenergic receptors.
分子量 | 332.4 |
公式 | C16H22N2O2.½C4H4O4 |
储存 | Desiccate at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 874882-92-5 |
PubChem ID | 45073435 |
InChI Key | MCHSBYUSDSJLAQ-WXXKFALUSA-N |
Smiles | [H]OC(=O)\C=C\C(=O)O[H].CC(C)NCC(O)COC1=CC=CC=C1N1C=CC=C1.CC(C)NCC(O)COC1=CC=CC=C1N1C=CC=C1 |
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参考文献是支持产品生物活性的出版物。
Waldmeier et al (1988) Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. Naunyn Schmiedebergs Arch.Pharmacol. 337 609 PMID: 2905765
关键词: Isamoltane hemifumarate, Isamoltane hemifumarate supplier, 5-HT1B, antagonist, Serotonin, Receptors, 0992, Tocris Bioscience
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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
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