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Jedi2

Cat. No. 6614 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Piezo1 channel activator
化学名： 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Jedi2

Jedi2 is a piezo1 channel activator. Promotes Ca2+ influx into HEK293 cells expressing Piezo1 channels. Elicits responses in mouse Piezo1-transfected, but not Piezo2-transfected cells.

化合物库 for Jedi2

Jedi2 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for Jedi2

分子量 208.23
公式 C10H8O3S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 651005-90-2
PubChem ID 2796026
InChI Key YXDCRSXNEOKXDE-UHFFFAOYSA-N
Smiles CC1=C(C(O)=O)C=C(C2=CC=CS2)O1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Jedi2

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 20.82 100
ethanol 20.82 100

制备储备液 for Jedi2

以下数据基于产品分子量 208.23。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.8 mL 24.01 mL 48.02 mL
5 mM 0.96 mL 4.8 mL 9.6 mL
10 mM 0.48 mL 2.4 mL 4.8 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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产品说明书 for Jedi2

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Jedi2

参考文献是支持产品生物活性的出版物。

Wang et al (2018) A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel. Nat.Commun. 9 1300 PMID: 29610524

If you know of a relevant reference for Jedi2, please let us know.

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关键词: Jedi2, Jedi2 supplier, Jedi2, Piezo1, calcium, channels, activators, activates, Ca2+, currents, mechanotransduction, mechanosensitive, Piezo, Channels, 6614, Tocris Bioscience

1 篇 Jedi2 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Jedi2 的部分引用包括：

Yuri et al (2021) Selective Chemical Activation of Piezo1 in Leukemia Cell Membrane: Single Channel Analysis. Int J Mol Sci 22 PMID: 34360605

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