Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewJWH 018
说明： Potent CB1 and CB2 agonist
化学名： (1-Pentyl-1H-indol-3-yl)-1-naphthalenylmethanone
纯度： ≥99% (HPLC)
生物活性 for JWH 018
Potent cannabinoid receptor agonist with mild selectivity for CB2 (Ki values are 2.94 and 9.0 nM for CB2 and CB1 receptors respectively).
技术数据 for JWH 018
| 分子量 | 341.45 |
| 公式 | C24H23NO |
| 储存 | Desiccate at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 209414-07-3 |
| PubChem ID | 10382701 |
| InChI Key | JDNLPKCAXICMBW-UHFFFAOYSA-N |
| Smiles | O=C(C3=CN(CCCCC)C4=C3C=CC=C4)C1=CC=CC2=C1C=CC=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for JWH 018
参考文献 for JWH 018
参考文献是支持产品生物活性的出版物。
Aung et al (2000) Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60 133 PMID: 10940540
Chin et al (1999) The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor. J.Pharmacol.Exp.Ther. 291 837 PMID: 10525107
Huffman et al (2003) 3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor. Bioorg.Med.Chem. 11 539 PMID: 12538019
按产品操作查看相关产品
关键词: JWH 018, JWH 018 supplier, Potent, CB1, CB2, agonists, Cannabinoids, Non-Selective, Receptors, JWH018, cb2r, cb1r, Non-selective, 1342, Tocris Bioscience
1 篇 JWH 018 的引用文献
引用文献是使用了 Tocris 产品的出版物。 JWH 018 的部分引用包括：
Ford (2017) Characterization of structurally novel G protein biased CB1 agonists: implications for drug development. Pharmacol Res 125 161 PMID: 28838808
JWH 018 的评论
目前没有该产品的评论。 Be the first to review JWH 018 and earn rewards!
Have you used JWH 018?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Cannabinoid Receptor Ligands Scientific Review
Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.