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Submit ReviewKisspeptin 10 (rat)
说明： Endogenous ligand for kisspeptin receptor
纯度： ≥95% (HPLC)
生物活性 for Kisspeptin 10 (rat)
Kisspeptin 10 (rat) is an endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54).
Human Analog also available.
技术数据 for Kisspeptin 10 (rat)
| 分子量 | 1318.45 |
| 公式 | C63H83N17O15 |
| 序列 | YNWNSFGLRY-NH2 |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 478507-53-8 |
| PubChem ID | 90488921 |
| InChI Key | HVPGTDOCSYBNFC-INXYWQKQSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Kisspeptin 10 (rat)
| 溶解性 | Soluble to 2 mg/ml in water |
产品说明书 for Kisspeptin 10 (rat)
参考文献 for Kisspeptin 10 (rat)
参考文献是支持产品生物活性的出版物。
Stafford et al (2002) Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res. 62 5399 PMID: 12359743
Navarro et al (2004) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 145 4565 PMID: 15242985
If you know of a relevant reference for Kisspeptin 10 (rat), please let us know.
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关键词: Kisspeptin 10 (rat), Kisspeptin 10 (rat) supplier, Endogenous, ligands, KISS1, receptors, hOT7T175/AXOR12/GPR54, Metastin, KISS-derived, Peptide, Kisspeptin10, Kisspeptin, Receptor, 4243, Tocris Bioscience
10 篇 Kisspeptin 10 (rat) 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Kisspeptin 10 (rat) 的部分引用包括：
Varykina G et al (2019) Insulin-induced hypoglycaemia suppresses pulsatile luteinising hormone secretion and arcuate Kiss1 cell activation in female mice. J Neuroendocrinol 31 e12813 PMID: 31758872
Pamela L et al (2019) Deletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting in Infertility. Endocrinology 160 2151-2164 PMID: 31211355
Tonsfeldt et al (2019) The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge. J Endocr Soc 3 716 PMID: 30906911
T John et al (2013) β-Arrestin 2 is a mediator of GnRH-(1-5) signaling in immortalized GnRH neurons. Endocrinology 154 4726-36 PMID: 24140715
Rogéria et al (2022) Kisspeptin treatment improves fetal-placental development and blocks placental oxidative damage caused by maternal hypothyroidism in an experimental rat model. Front Endocrinol (Lausanne) 13 908240 PMID: 35966095
Pamela L et al (2022) Female fertility does not require Bmal1 in suprachiasmatic nucleus neurons expressing arginine vasopressin, vasoactive intestinal peptide, or neuromedin-S. Front Endocrinol (Lausanne) 13 956169 PMID: 35992114
Schoeller et al (2016) Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. Endocrinology 157 4914 PMID: 27704948
Pineda et al (2016) Amygdala Kisspeptin Neurons: Putative Mediators of Olfactory Control of the Gonadotropic Axis. Neuroendocrinology 104 223 PMID: 27054958
Juneo Freitas et al (2023) Kisspeptin Suppresses Inflammasome-NLRP3 Activation and Pyroptosis Caused by Hypothyroidism at the Maternal-Fetal Interface of Rats. Int J Mol Sci 24 PMID: 37047793
Duong et al (2021) The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. J Neurosci Res 99 2625-2645 PMID: 34212416
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