Kynurenic acid sodium salt

Pricing Availability   Qty
说明: Sodium salt of kynurenic acid (Cat. No. 0223)
化学名: 4-Hydroxyquinoline-2-carboxylic acid sodium salt
纯度: ≥98% (HPLC)
说明书
引用文献 (2)
评论
文献 (1)

生物活性 for Kynurenic acid sodium salt

Kynurenic acid sodium salt is a sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

化合物库 for Kynurenic acid sodium salt

Kynurenic acid sodium salt is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for Kynurenic acid sodium salt

分子量 211.15
公式 C10H6NNaO3
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 2439-02-3
PubChem ID 52974250
InChI Key RCAZGXKUQDXSSK-UHFFFAOYSA-M
Smiles [Na+].OC1=CC(=NC2=CC=CC=C12)C([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Kynurenic acid sodium salt

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 21.11 100
DMSO 10.56 50

制备储备液 for Kynurenic acid sodium salt

以下数据基于产品分子量 211.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.74 mL 23.68 mL 47.36 mL
5 mM 0.95 mL 4.74 mL 9.47 mL
10 mM 0.47 mL 2.37 mL 4.74 mL
50 mM 0.09 mL 0.47 mL 0.95 mL

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产品说明书 for Kynurenic acid sodium salt

分析证书/产品说明书
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参考文献 for Kynurenic acid sodium salt

参考文献是支持产品生物活性的出版物。

Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184 PMID: 6215086

Pittaluga et al (1997) The 'kynurenate test', a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82 PMID: 9336311

Wang et al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021 PMID: 16754668

Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Progr.Neurobiol. 30 333 PMID: 2830636


If you know of a relevant reference for Kynurenic acid sodium salt, please let us know.

关键词: Kynurenic acid sodium salt, Kynurenic acid sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, GPR35, 3694, Tocris Bioscience

2 篇 Kynurenic acid sodium salt 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Kynurenic acid sodium salt 的部分引用包括:

Ruilong et al (2021) Long-Range GABAergic Inhibition Modulates Spatiotemporal Dynamics of the Output Neurons in the Olfactory Bulb. J Neurosci 41 3610-3621 PMID: 33687961

Stefano et al (2022) Brainstem activation of GABAB receptors in the nucleus tractus solitarius increases gastric motility. Front Neurosci 16 961042 PMID: 35983226


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