L-703,664 succinate

Name: L-703,664 succinate
Brand: Tocris Bioscience
SKU: 2640

Cat. No. 2640 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2640 has been discontinued.

View all 5-HT<sub>1D</sub> Receptors products.

说明： Selective 5-HT_1D agonist

化学名： N,N-Dimethyl-5-[(5-methyl-1,1-dioxodo-1,2,5-thiadiazolidin-2-yl)methyl]-1H-indole-3-ethanamine succinate

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for L-703,664 succinate

L-703,664 succinate is a 5-HT_1D receptor agonist that displays selectivity over other 5-HT receptor subtypes (pIC₅₀ values are 7.2, 6.1, < 5.0 and < 5.0 for 5-HT_1D, 5-HT_1A, 5-HT_2A and 5-HT₃ respectively) and other receptors (pIC₅₀ < 5.0 for adenosine, adrenergic, excitatory amino acids, dopamine, histamine, muscarinic, nicotinic and opiate receptors).

许可信息

Sold with the permission of Merck, Sharpe and Dohme Ltd.

技术数据 for L-703,664 succinate

分子量	454.54
公式	C₁₆H₂₄N₄O₂S.C₄H₆O₄
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	144776-01-2
PubChem ID	90488774
InChI Key	WLXRLNXDMGIORD-UHFFFAOYSA-N
Smiles	O=S1(N(CCN1C)CC2=CC=C(NC=C3CCN(C)C)C3=C2)=O.O=C(CCC(O)=O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for L-703,664 succinate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for L-703,664 succinate

参考文献是支持产品生物活性的出版物。

Castro et al (1994) Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin-2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT_1D receptor. J.Med.Chem. 37 3023 PMID: 7932524

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关键词: L-703,664 succinate, L-703,664 succinate supplier, Selective, 5-HT1D, receptor, agonists, Serotonin, Receptors, L703664, 2640, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.