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Submit ReviewL-Dehydroascorbic acid
说明： GLUT1 substrate; oxidized form of L-Ascorbic acid
化学名： L-threo-2,3-Hexodiulosonic acid γ-lactone
生物活性 for L-Dehydroascorbic acid
L-Dehydroascorbic acid is a oxidized form of L-Ascorbic acid (Cat. No. 4055). Transported into cells through GLUT1. Selectively induces cell death in KRAS and BRAF mutant cells in vitro.
技术数据 for L-Dehydroascorbic acid
| 分子量 | 174.11 |
| 公式 | C6H6O6 |
| 储存 | Store at -20°C |
| CAS Number | 490-83-5 |
| PubChem ID | 440667 |
| InChI Key | SBJKKFFYIZUCET-JLAZNSOCSA-N |
| Smiles | O=C1C([C@]([C@@H](O)CO)([H])OC1=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for L-Dehydroascorbic acid
参考文献 for L-Dehydroascorbic acid
参考文献是支持产品生物活性的出版物。
Kaiser (2015) Vitamin C could target some common cancers. Science 6 6261 PMID: 26542550
Yun et al (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science 11 6266 PMID: 26541605
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关键词: L-Dehydroascorbic acid, L-Dehydroascorbic acid supplier, vitamin, vit, C, oxidised, form, L-Ascorbic, acid, GLUT1, glucose, transporters, KRAS, BRAF, Glucose, Transporters, Antioxidants, 5734, Tocris Bioscience
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