Latrunculin B

Cat. No. 3974 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Inhibitor of actin polymerization

化学名： (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone

纯度： ≥95% (HPLC)

引用文献 (5)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Latrunculin B

Latrunculin B is an inhibitor of actin polymerization. Interacts with G-actin in a 1:1 ratio to inhibit polymerization into F-actin in vitro (IC₅₀ values are ~60 and ~900 nM in absence and presence of calf serum, respectively). Marine toxin.

技术数据 for Latrunculin B

分子量	395.51
公式	C₂₀H₂₉NO₅S
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	76343-94-7
PubChem ID	3892
InChI Key	NSHPHXHGRHSMIK-UHFFFAOYSA-N
Smiles	O=C1/C=C(C)\CC/C=C\[C@@H](C)CC[C@@H]2C[C@H](C[C@](O)([C@@]3([H])NC(SC3)=O)O2)O1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Latrunculin B

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	19.78	50
	ethanol	19.78	50

制备储备液 for Latrunculin B

以下数据基于产品分子量 395.51。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.5 mM	5.06 mL	25.28 mL	50.57 mL
2.5 mM	1.01 mL	5.06 mL	10.11 mL
5 mM	0.51 mL	2.53 mL	5.06 mL
25 mM	0.1 mL	0.51 mL	1.01 mL

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产品说明书 for Latrunculin B

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Latrunculin B

参考文献是支持产品生物活性的出版物。

Wakatsuki et al (2001) Effects of cytochalasin D and latrunculin B on mechanical properties of cells. J.Cell.Sci. 114 1025 PMID: 11181185

If you know of a relevant reference for Latrunculin B, please let us know.

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关键词: Latrunculin B, Latrunculin B supplier, Inhibitors, Inhibits, Actin, filament, modulator, G-Actin, F-Actin, monomers, polymers, toxin, 3974, Tocris Bioscience