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LDV

Cat. No. 7020 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： α4β1 (VLA-4) ligand
纯度： ≥95% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for LDV

LDV is a α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC (Cat. No. 4577).

技术数据 for LDV

分子量 979.13
公式 C48H70N10O12
序列 LDVPAAK (Modifications: Leu-1 = N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-Leu)
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 1155866-55-9
InChI Key FQYZPSNPTJYQKB-CGTMUHGOSA-N
Smiles CC(C)C[C@@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)C)=O)C)=O)=O)C(C)C)=O)CC(O)=O)=O)NC(CC(C=C2)=CC=C2NC(NC3=C(C)C=CC=C3)=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for LDV

溶解性 Soluble to 1 mg/ml in 0.01M PBS (pH 7.4)

产品说明书 for LDV

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化学品安全技术说明书

参考文献 for LDV

参考文献是支持产品生物活性的出版物。

Chigaev et al (2009) Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. J.Biol.Chem. 284 14337 PMID: 19251697

If you know of a relevant reference for LDV, please let us know.

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关键词: LDV, LDV supplier, VLA4, very, late, antigen, 4, ligand, integrin, a4b1, alpha4beta1, Integrins, 7020, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Angiogenesis in Cancer Poster

Angiogenesis in Cancer Poster

This poster summarizes the pathogenesis of angiogenesis in cancer, as well as some of the main angiogenesis therapeutic targets.

Enabling Research By Provision of Chemical Tools Poster

Enabling Research By Provision of Chemical Tools Poster

The Tocris chemistry team has considerable chemistry knowledge and skill which it has recently been applying to the generation of new chemical probes from known tools and compounds to help answer biological questions. This poster presents some of the work carried out by Tocris scientists and focuses on two areas: the generation of libraries of chemical building blocks to support Degrader (PROTAC) research and the development of a fluorescent probe to study integrin biology. Presented at Chemical Tools for Complex Biological Systems II, 2019, Janelia Research Campus, USA.