Leukotriene B₄

Cat. No. 2307 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： BLT₁/BLT₂ receptor agonist and potent chemotactic factor

别名： LTB₄,5,12-DiHETE

化学名： (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosatetraenoic acid

纯度： ≥95% (HPLC)

引用文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Leukotriene B₄

Leukotriene B₄ is a potent lipid inflammatory mediator derived from the 5-lipoxygenase pathway of arachidonic acid metabolism. Binds to BLT₁ and BLT₂ receptors and acts as a potent chemotactic agent and activator of leukocytes. Also displays antiviral activity towards DNA viruses and retroviruses.

技术数据 for Leukotriene B₄

分子量	336.47
公式	C₂₀H₃₂O₄
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	71160-24-2
PubChem ID	5280492
InChI Key	VNYSSYRCGWBHLG-AMOLWHMGSA-N
Smiles	O[C@@H](CCCC(O)=O)\C=C/C=C/C=C/[C@H](O)C/C=C\CCCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Leukotriene B₄

溶解性	Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 50µg/ml)

产品说明书 for Leukotriene B₄

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Leukotriene B₄

参考文献是支持产品生物活性的出版物。

Bray et al (1981) Leukotriene B4: an inflammatory mediator in vivo. Prostaglandins 22 213 PMID: 6270742

Ford-Hutchinson (1990) Leukotriene B4 in inflammation. Crit.Rev.Immunol. 10 1 PMID: 2155000

Yokomitso et al (2001) Leukotriene B₄: metabolism and signal transduction. Arch.Biochem.Biophys. 385 231 PMID: 11368003

If you know of a relevant reference for Leukotriene B₄, please let us know.

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关键词: Leukotriene B4, Leukotriene B4 supplier, BLT1, BLT2, receptor, agonists, potent, Receptors, leukotrienes, eicosanoids, LeukotrieneB4, LTB4, 5,12-DiHETE, Leukotriene, and, Related, Non-selective, Antivirals, 2307, Tocris Bioscience

1 篇 Leukotriene B₄ 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Leukotriene B₄ 的部分引用包括：

Fernandes et al (2013) Superoxide generation and leukocyte accumulation: key elements in the mediation of leukotriene B4-induced itch by transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1. FASEB J 27 1664 PMID: 23271050

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