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Submit ReviewLeuprolide
Discontinued Product
2873 has been discontinued.
View all Gonadotropin-Releasing Hormone Receptors products.
说明： GnRH receptor agonist
别名： Leuoprorelin
生物活性 for Leuprolide
Leuprolide is a gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.
技术数据 for Leuprolide
| 分子量 | 1209.41 |
| 公式 | C59H84N16O12 |
| 序列 |
XHWSYLLRP (Modifications: X1 = Glp, Pro-9 = Pro-NHEt) |
| 储存 | Desiccate at -20°C |
| CAS Number | 53714-56-0 |
| PubChem ID | 90488782 |
| InChI Key | GFIJNRVAKGFPGQ-UILVTTEASA-N |
| Smiles | [H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Leuprolide
参考文献 for Leuprolide
参考文献是支持产品生物活性的出版物。
Okada et al (1988) One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 244 744 PMID: 3126294
Uday et al (2007) LHRH antagonist attenuates the effect of fluox. on marble-burying behavior in mice. Eur.J.Pharmacol. 563 155 PMID: 17368614
Salvador et al (2001) Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leupr. on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol. 37 641
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关键词: Leuprolide, Leuprolide supplier, GnRH, receptor, agonists, Receptors, Gonadotrophin-Releasing, Hormone, gonadotropin, chemotherapeutics, Leuoprorelin, 2873, Tocris Bioscience
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