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Lidocaine

Cat. No. 3057 2 篇引用文献 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Na+ channel blocker
化学名： 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
纯度： ≥99% (HPLC)
说明书
引用文献 (2)
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Lidocaine

Lidocaine is an anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.

技术数据 for Lidocaine

分子量 234.34
公式 C14H22N2O
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 137-58-6
PubChem ID 3676
InChI Key NNJVILVZKWQKPM-UHFFFAOYSA-N
Smiles O=C(CN(CC)CC)NC1=C(C)C=CC=C1C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Lidocaine

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 23.43 100
DMSO 23.43 100

制备储备液 for Lidocaine

以下数据基于产品分子量 234.34。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.27 mL 21.34 mL 42.67 mL
5 mM 0.85 mL 4.27 mL 8.53 mL
10 mM 0.43 mL 2.13 mL 4.27 mL
50 mM 0.09 mL 0.43 mL 0.85 mL

Molarity Calculator

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产品说明书 for Lidocaine

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Lidocaine

参考文献是支持产品生物活性的出版物。

Sarraf et al (2003) Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats. Br.J.Pharmacol. 139 1389 PMID: 12922925

If you know of a relevant reference for Lidocaine, please let us know.

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关键词: Lidocaine, Lidocaine supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Voltage-gated, 3057, Tocris Bioscience

2 篇 Lidocaine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Lidocaine 的部分引用包括：

Miguel Angel Garcia-Bereguiain et al (2016) Spontaneous Release Regulates Synaptic Scaling in the Embryonic Spinal Network In Vivo The Journal of Neuroscience 6 7268 PMID: 27383600

Hernández-Cascales (2017) Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium. PeerJ 5 e3113 PMID: 28382232

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Lidocaine 的评论

平均评分: 5 (Based on 1 Review.)

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Lidocaine in prelimbic medial prefrontal cortex blocks cue-induced reinstatement of MDMA seeking.
By Kevin Ball on 01/25/2019
分析类型： In Vivo
种属： Rat

Bilateral microinjections of lidocaine (100 micrograms/0.5 microliter/side) into prelimbic, but not infralimbic, medial prefrontal cortex blocked cue-induced reinstatement of MDMA (ecstasy)-seeking behavior compared with saline microinjections into the same region. Lidocaine microinjections into either region did not, however, have an effect on food-maintained responding, ruling out a nonspecific disruption of motor performance.

PMID: 4078904 参考文献
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