Voltage-gated Sodium (NaV) Channel Blockers
| Cat. No. | Product Name / Activity |
|---|---|
| 2976 | A 803467 |
| Selective NaV1.8 channel blocker | |
| 4249 | A 887826 |
| Potent voltage-dependent NaV1.8 channel blocker | |
| 0890 | Amiloride hydrochloride |
| Na+ channel blocker; also I2 imidazoline ligand | |
| 4804 | APETx2 |
| NaV1.8 and NaV1.2 blocker; also blocks ASIC3 channels | |
| 4098 | Carbamazepine |
| Inhibitor of neuronal NaV channels; anticonvulsant | |
| 1470 | Flecainide acetate |
| Cardiac Na+ channel blocker. Antiarrhythmic | |
| 7029 | GX 201 |
| Potent and selective Nav1.7 blocker; analgesic | |
| 5066 | ICA 121431 |
| Potent and selective NaV1.3 and NaV1.1 channel blocker | |
| 4913 | Jingzhaotoxin III |
| Selective NaV1.5 channel blocker | |
| 3865 | Licarbazepine |
| Active metabolite of oxcarbazepine (Cat. No. 3864) | |
| 3057 | Lidocaine |
| Na+ channel blocker | |
| 2596 | Mexiletine hydrochloride |
| Na+ channel blocker; antiarrhythmic agent | |
| 5927 | NS 383 |
| ASIC blocker; active in vivo | |
| 3864 | Oxcarbazepine |
| Anticonvulsant; inhibits Na+ channel activity | |
| 4916 | PF 04885614 |
| Potent and selective NaV1.8 channel blocker; active in vivo | |
| 5931 | PF 05089771 |
| Potent and selective Nav1.7 channel blocker | |
| 4914 | Phrixotoxin 3 |
| Potent blocker of NaV1.2, NaV1.3 and NaV1.5 channels | |
| 4023 | ProTx II |
| Selective NaV1.7 channel blocker | |
| 1014 | QX 314 bromide |
| Na+ channel blocker | |
| 2313 | QX 314 chloride |
| Na+ channel blocker | |
| 0768 | Riluzole hydrochloride |
| Na+ channel blocker; also inhibits GABA uptake and glutamate release | |
| 4044 | Sipatrigine |
| NaV blocker; neuroprotective | |
| 4435 | TC-N 1752 |
| NaV channel blocker | |
| 1078 | Tetrodotoxin |
| Na+ channel blocker | |
| 1069 | Tetrodotoxin citrate |
| Na+ channel blocker; citrate salt of tetrodotoxin (Cat. No. 1078) | |
| 2815 | Valproic acid, sodium salt |
| Blocks voltage-gated Na+ channels |