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Submit Review生物活性 for LRGILS-NH2
LRGILS-NH2 is a reversed amino acid sequence control peptide for SLIGRL-NH2, a protease-activated receptor-2 (PAR2) agonist that facilitates gastrointestinal transit in vivo.
Active Analog also available.
技术数据 for LRGILS-NH2
| 分子量 | 656.83 |
| 公式 | C29H56N10O7 |
| 序列 |
LRGILS (Modifications: Ser-6 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 245329-01-5 |
| PubChem ID | 90488840 |
| InChI Key | HCUFWKYFOMBFPA-JYAZKYGWSA-N |
| Smiles | [H]N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for LRGILS-NH2
| 溶解性 | Soluble to 2 mg/ml in water |
产品说明书 for LRGILS-NH2
参考文献 for LRGILS-NH2
参考文献是支持产品生物活性的出版物。
Tognetto et al (2000) Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder. Br.J.Pharmacol. 131 689 PMID: 11030717
Nishikawa et al (2005) Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in Rats: Involvement of PAR-2 and non-PAR-2 mechanisms. J.Pharmacol.Exp.Ther. 312 324 PMID: 15331653
Devlin et al (2007) Initial support for the hypothesis that PAR2 is involved in the immune response to Nippostrongylus brasiliensis in mice. Parasitol.Res. 101 105 PMID: 17458579
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关键词: LRGILS-NH2, LRGILS-NH2 supplier, Control, peptide, SLIGRL-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3394, Tocris Bioscience
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LRGILS-NH2 的评论
平均评分: 4 (Based on 1 Review.)
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Good and easy product to use for regular in-vitro stimulations.
By
Anonymous on 11/20/2019
分析类型： In Vitro
种属： Human
细胞系/组织： Smooth Muscle Cells
Was used in an in-vitro stimulation assay as a control peptide