LY 288513

Cat. No. 1524 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Selective CCK₂ antagonist

化学名： (4S,5R)-N-(4-Bromophenyl)-3-oxo-4,5-diphenyl-1-pyrazolidinecarboxamide

纯度： ≥98% (HPLC)

引用文献 (1)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for LY 288513

LY 288513 is a selective CCK₂ receptor antagonist (IC₅₀ values are 16 and > 30,000 nM for CCK₂ and CCK₁ respectively). Displays anxiolytic and antipsychotic properties in vivo.

许可信息

Sold with the permission of Eli Lilly and Company

技术数据 for LY 288513

分子量	436.3
公式	C₂₂H₁₈BrN₃O₂
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	147523-65-7
PubChem ID	2802894
InChI Key	LMUQHXHWJWQXSD-PMACEKPBSA-N
Smiles	BrC1=CC=C(NC(=O)N2NC(=O)[C@H]([C@@H]2C2=CC=CC=C2)C2=CC=CC=C2)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for LY 288513

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	43.63	100

制备储备液 for LY 288513

以下数据基于产品分子量 436.3。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.29 mL	11.46 mL	22.92 mL
5 mM	0.46 mL	2.29 mL	4.58 mL
10 mM	0.23 mL	1.15 mL	2.29 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for LY 288513

分析证书/产品说明书

化学品安全技术说明书

参考文献 for LY 288513

参考文献是支持产品生物活性的出版物。

Rasmussen (1994) CCK, schizophrenia, and anxiety. CCK-B antagonists inhibit the activity of brain DA neurons. Ann.N.Y.Acad.Sci. 713 300 PMID: 8185172

Helton et al (1996) Central nervous system characterization of the new cholecystokininB antagonist LY288513. Pharmacol.Biochem.Behav. 53 493 PMID: 8866946

Rasmussen et al (1992) Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain DA neurons. J.Pharmacol.Exp.Ther. 264 480

If you know of a relevant reference for LY 288513, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 CCK₂ Receptor Antagonists

关键词: LY 288513, LY 288513 supplier, Selective, CCK2, antagonists, Cholecystokinin2, Receptors, LY288513, Receptor, 1524, Tocris Bioscience

1 篇 LY 288513 的引用文献

引用文献是使用了 Tocris 产品的出版物。 LY 288513 的部分引用包括：

Wen et al (2012) Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular mor. dependence. Front Endocrinol (Lausanne) 13 63 PMID: 22682150

您是否知道使用了 Tocris LY 288513 的优秀论文？请告知我们.

LY 288513 的评论

目前没有该产品的评论。 Be the first to review LY 288513 and earn rewards!

Have you used LY 288513?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.