MDL 12330A hydrochloride

Name: MDL 12330A hydrochloride
Brand: Tocris Bioscience
SKU: 1436

Cat. No. 1436 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1436 has been discontinued.

View all Adenylyl Cyclases products.

说明： Adenylyl cyclase inhibitor; also cyclic nucleotide PDE inhibitor

化学名： (±)-N-[(1R*,2R*)-2-Phenylcyclopentyl]-azacyclotridec-1-en-2-amine hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献 (2)

生物活性技术数据说明书参考文献

生物活性 for MDL 12330A hydrochloride

MDL 12330A hydrochloride is an inhibitor of adenylyl cyclase. Also inhibits cAMP and cGMP phosphodiesterases, and blocks slow extracellular and store-operated Ca²⁺ entry into cells.

技术数据 for MDL 12330A hydrochloride

分子量	377.01
公式	C₂₃H₃₆N₂.HCl
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	40297-09-4
PubChem ID	6917816
InChI Key	CKOPQUCSDBVAQG-VROPFNGYSA-N
Smiles	C1(/N[C@@H]2[C@H]([C@]3=CC=CC=C3)CCC2)=N\CCCCCCCCCCC1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for MDL 12330A hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for MDL 12330A hydrochloride

参考文献是支持产品生物活性的出版物。

Guellaen et al (1977) RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. Biochim.Biophys.Acta 484 465 PMID: 911855

Hunt and Evans (1980) RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate cyclase in kidney preparations. Biochim.Biophys.Acta 613 499 PMID: 6256001

van Rossum et al (2000) Ca²⁺ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function. J.Biol.Chem. 275 28562 PMID: 10878007

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关键词: MDL 12330A hydrochloride, MDL 12330A hydrochloride supplier, adenylyl, cyclase, cyclic, AMP, GMP, cAMP, cGMP, PDE, phosphodiesterases, store-operated, store, operated, calcium, SOCE, channels, MDL12330A, Adenylyl, Cyclase, Phosphodiesterases, General, Calcium, Signaling, Agents, 1436, Tocris Bioscience

2 篇 MDL 12330A hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 MDL 12330A hydrochloride 的部分引用包括：

Pietak et al (2019) Neural control of body-plan axis in regenerating planaria. PLoS Comput Biol 15 e1006904 PMID: 30990801

Li et al (2017) Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics 7 4671 PMID: 29187895