MDNI-caged-L-glutamate

Name: MDNI-caged- L -glutamate
Brand: Tocris Bioscience
SKU: 5785

Cat. No. 5785 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

This product has been withdrawn from sale and is superseded by MNI-caged-L-glutamate (Cat. No. 1490)

说明： Stable photoreleaser of L-glutamate

别名： caged MDNI glutamate,DNI glutamate,DNI-GLU

化学名： (S)-α-Amino-2,3-dihydro-4-methoxy-5,7-dinitro-δ-oxo-1H-indole-1-pentanoic acid

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (3)

生物活性技术数据说明书参考文献

生物活性 for MDNI-caged-L-glutamate

Rapidly and efficiently releases glutamate (Cat. No. 0218) when photolysed (350 - 365 nm excitation). Water soluble and stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to 200 μM). 5.5 times more photosensitive than MNI-caged L-glutamate (Cat. No. 1490). Laser activation of MDNI-glu evokes a rapid increase in intracellular Ca²⁺ concentration in astrocytes.

Important information for MDNI-caged-L-glutamate

As a result of the manufacturing process, this product contains some residual TFA. The amount of TFA is batch dependant and will appear in the batch molecular formula.

技术数据 for MDNI-caged-L-glutamate

分子量	368.3
公式	C₁₄H₁₆N₄O₈
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	864085-92-7
PubChem ID	124221751
InChI Key	SYNWQVVPBORTQE-QMMMGPOBSA-N
Smiles	O=C(CC[C@H](N)C(O)=O)N1C2=C([N+]([O-])=O)C=C([N+]([O-])=O)C(OC)=C2CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for MDNI-caged-L-glutamate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for MDNI-caged-L-glutamate

参考文献是支持产品生物活性的出版物。

Fedoryak et al (2005) Synthesis of a caged glutamate for efficient one- and two-photon photorelease on living cells. Chem. Commun. (Camb.) 7 3664 PMID: 16027904

Papageorgiou et al (2005) Synthetic and photochemical studies of substituted 1-acyl-7-nitroindolines. Photochem.Photobiol.Sci. 4 887 PMID: 16252044

Popovic et al (2015) Electrical behaviour of dendritic spines as revealed by voltage imaging. Nat.Commun. 6 8436 PMID: 26436431

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关键词: MDNI-caged-L-glutamate, MDNI-caged-L-glutamate supplier, Stable, photoreleaser, L-glutamate, Caged, Compounds, Glutamate, mGlur, Receptors, Metabotropic, Non-Selective, iGlur, Ionotropic, agonists, MNI, glutamate, MNI-Glutamate, caged, MDNI, DNI, DNI-GLU, Miscellaneous, Non-selective, mGlu, 5785, Tocris Bioscience

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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

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