Methylergometrine maleate

Pricing Availability   Qty
说明: Active metabolite of methysergide (Cat. No. 1064)
别名: Methylergonovine maleate
化学名: [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate
纯度: ≥98% (HPLC)
说明书
引用文献 (2)
评论
文献 (2)

生物活性 for Methylergometrine maleate

Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.

技术数据 for Methylergometrine maleate

分子量 455.51
公式 C20H25N3O2.C4H4O4
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 57432-61-8
PubChem ID 5281072
InChI Key NOFOWWRHEPHDCY-DAUURJMHSA-N
Smiles OC(=O)\C=C/C(O)=O.[H][C@](CC)(CO)NC(=O)[C@@]1([H])CN(C)[C@]2([H])CC3=CNC4=C3C(=CC=C4)C2=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Methylergometrine maleate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 25

制备储备液 for Methylergometrine maleate

以下数据基于产品分子量 455.51。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.25 mM 8.78 mL 43.91 mL 87.81 mL
1.25 mM 1.76 mL 8.78 mL 17.56 mL
2.5 mM 0.88 mL 4.39 mL 8.78 mL
12.5 mM 0.18 mL 0.88 mL 1.76 mL

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产品说明书 for Methylergometrine maleate

参考文献 for Methylergometrine maleate

参考文献是支持产品生物活性的出版物。

MacLennan and Martin (1990) Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 342 120 PMID: 2234096

Muller-Schweinitzer and Tapparelli (1986) Methylergometrine, an active metabolite of methysergide. Cephalalgia 6 35 PMID: 3698092

Pertz (1993) 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 348 558 PMID: 8133899

Merck Index 12 6147


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按标靶查看相关产品

关键词: Methylergometrine maleate, Methylergometrine maleate supplier, Active, metabolite, methysergide, Serotonin, 5-HT-, 5-Hydroxytryptamine, Receptors, 5-HT, 5-HT1, 5-HT2, antagonists, Methylergonovine, maleate, Non-selective, 0549, Tocris Bioscience

2 篇 Methylergometrine maleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Methylergometrine maleate 的部分引用包括:

Murray et al (2011) Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol 106 925 PMID: 21653728

Chan et al (2015) Ergot Alkaloids (Re)generate New Leads as Antiparasitics. Cell Signal 9 e0004063 PMID: 26367744


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