Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMethylergometrine maleate
说明： Active metabolite of methysergide (Cat. No. 1064)
别名： Methylergonovine maleate
化学名： [8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-6-methylergoline-8-carboxamide maleate
纯度： ≥98% (HPLC)
生物活性 for Methylergometrine maleate
Methylergometrine maleate is an active metabolite of methysergide (Cat. No. 1064); uterotonic agent and oxytocic.
技术数据 for Methylergometrine maleate
| 分子量 | 455.51 |
| 公式 | C20H25N3O2.C4H4O4 |
| 储存 | Desiccate at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 57432-61-8 |
| PubChem ID | 5281072 |
| InChI Key | NOFOWWRHEPHDCY-DAUURJMHSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.[H][C@](CC)(CO)NC(=O)[C@@]1([H])CN(C)[C@]2([H])CC3=CNC4=C3C(=CC=C4)C2=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Methylergometrine maleate
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 25 |
制备储备液 for Methylergometrine maleate
以下数据基于产品分子量 455.51。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 8.78 mL | 43.91 mL | 87.81 mL |
| 1.25 mM | 1.76 mL | 8.78 mL | 17.56 mL |
| 2.5 mM | 0.88 mL | 4.39 mL | 8.78 mL |
| 12.5 mM | 0.18 mL | 0.88 mL | 1.76 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
产品说明书 for Methylergometrine maleate
参考文献 for Methylergometrine maleate
参考文献是支持产品生物活性的出版物。
MacLennan and Martin (1990) Actions of non-peptide ergot alkaloids at 5-HT1-like and 5-HT2 receptors mediating vascular smooth muscle contraction. Naunyn Schmiedebergs Arch.Pharmacol. 342 120 PMID: 2234096
Muller-Schweinitzer and Tapparelli (1986) Methylergometrine, an active metabolite of methysergide. Cephalalgia 6 35 PMID: 3698092
Pertz (1993) 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors. Naunyn Schmiedebergs Arch.Pharmacol. 348 558 PMID: 8133899
Merck Index 12 6147
If you know of a relevant reference for Methylergometrine maleate, please let us know.
按标靶查看相关产品
关键词: Methylergometrine maleate, Methylergometrine maleate supplier, Active, metabolite, methysergide, Serotonin, 5-HT-, 5-Hydroxytryptamine, Receptors, 5-HT, 5-HT1, 5-HT2, antagonists, Methylergonovine, maleate, Non-selective, 0549, Tocris Bioscience
2 篇 Methylergometrine maleate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Methylergometrine maleate 的部分引用包括：
Murray et al (2011) Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. J Neurophysiol 106 925 PMID: 21653728
Chan et al (2015) Ergot Alkaloids (Re)generate New Leads as Antiparasitics. Cell Signal 9 e0004063 PMID: 26367744
您是否知道使用了 Tocris Methylergometrine maleate 的优秀论文？ 请告知我们.
Methylergometrine maleate 的评论
目前没有该产品的评论。 Be the first to review Methylergometrine maleate and earn rewards!
Have you used Methylergometrine maleate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.