Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewMetoprolol tartrate
说明： Selective β1 antagonist
化学名： 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate
纯度： ≥99% (HPLC)
生物活性 for Metoprolol tartrate
Metoprolol tartrate is a selective β1-adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1, β2 and β3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.
化合物库 for Metoprolol tartrate
Metoprolol tartrate is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。
技术数据 for Metoprolol tartrate
| 分子量 | 342.4 |
| 公式 | C15H25NO3.½C4H6O6 |
| 储存 | Desiccate at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 56392-17-7 |
| PubChem ID | 6420057 |
| InChI Key | YGULWPYYGQCFMP-UHFFFAOYSA-N |
| Smiles | O=C(O)C(O)C(O)C(O)=O.OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.OC(CNC(C)C)COC2=CC=C(CCOC)C=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Metoprolol tartrate
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 34.24 | 100 | |
| DMSO | 34.24 | 100 |
制备储备液 for Metoprolol tartrate
以下数据基于产品分子量 342.4。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.92 mL | 14.6 mL | 29.21 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.92 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
产品说明书 for Metoprolol tartrate
参考文献 for Metoprolol tartrate
参考文献是支持产品生物活性的出版物。
Garlichs et al (1999) Beta-blockers reduce the release and synthesis of endothelin-1 in human endothelial cells. Eur.J.Clin.Invest. 29 12 PMID: 10092983
Dasbiswas et al (2008) S-metoprolol: The 2008 Clinical Review. J.Indian.Med.Assoc. 106 259 PMID: 18828349
Hoffmann et al (2004) Comparative pharmacology of human β-adrenergic receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmied.Arch.Pharmacol. 369 151 PMID: 14730417
If you know of a relevant reference for Metoprolol tartrate, please let us know.
按产品操作查看相关产品
关键词: Metoprolol tartrate, Metoprolol tartrate supplier, Selective, α1-adrenoceptor, beta1-adrenoceptor, b1-adrenoceptor, antagonists, b1-adrenergic, β1-Adrenergic, beta1-Adrenergic, Receptors, Adrenergic, Beta-1, 3256, Tocris Bioscience
篇 Metoprolol tartrate 的引用文献
引用文献是使用了 Tocris 产品的出版物。
目前没有 Metoprolol tartrate 的引用文献。 您是否知道使用了 Tocris Metoprolol tartrate 的优秀论文？ 请告知我们.
Metoprolol tartrate 的评论
目前没有该产品的评论。 Be the first to review Metoprolol tartrate and earn rewards!
Have you used Metoprolol tartrate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.