Miconazole nitrate

Name: Miconazole nitrate
Brand: Tocris Bioscience
SKU: 3016

Cat. No. 3016 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3016 has been discontinued.

View all Antifungals products.

说明： Azole antifungal agent

化学名： 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Miconazole nitrate

Miconazole nitrate is a antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species. Enhances the generation of mature oligodendrocytes from progenitor cells in vitro and promotes myelination in vivo. Attenuates disease severity in a mouse model of multiple sclerosis. Brain penetrant.

化合物库 for Miconazole nitrate

Miconazole nitrate is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Miconazole nitrate

分子量	479.14
公式	C₁₈H₁₄Cl₄N₂O.HNO₃
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	22832-87-7
PubChem ID	68553
InChI Key	MCCACAIVAXEFAL-UHFFFAOYSA-N
Smiles	ClC1=CC(Cl)=CC=C1COC(CN3C=CN=C3)C2=CC=C(Cl)C=C2Cl.O[N+]([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Miconazole nitrate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Miconazole nitrate

参考文献是支持产品生物活性的出版物。

Chang et al (2005) Effect of miconazole on intracellular Ca²⁺ levels and proliferation in human osteosarcoma cells. Life Sci. 76 2091 PMID: 15826876

Najim et al (2015) Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature 522 216 PMID: 25896324

Hubler et al (2018) Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. Nature 560 372 PMID: 30046109

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篇 Miconazole nitrate 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Miconazole nitrate 的引用文献。