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Misoprostol

Cat. No. 2297 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2297 has been discontinued.

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说明： Cytoprotective PGE1 analog
化学名： (±)-(11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic acid methyl ester
纯度： ≥99% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Misoprostol

Misoprostol is a cytoprotective prostaglandin E1 analog that displays agonist activity at EP receptors. Ki values are 120, 250, 67 and 67 nM at cloned mouse EP1, EP2, EP3 and EP4 receptors respectively. Prevents NSAID-induced gastric ulceration.

技术数据 for Misoprostol

分子量 382.53
公式 C22H38O5
储存 Desiccate at -20°C
纯度 ≥99% (HPLC)
CAS Number 59122-46-2
PubChem ID 5282381
InChI Key OJLOPKGSLYJEMD-URPKTTJQSA-N
Smiles O[C@@H]1CC([C@H](CCCCCCC(OC)=O)[C@H]1/C=C/CC(O)(C)CCCC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Misoprostol

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化学品安全技术说明书

参考文献 for Misoprostol

参考文献是支持产品生物活性的出版物。

Graham et al (1988) Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial. Lancet 2 1277 PMID: 2904006

Smith et al (1994) Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus. J.Pharmacol.Exp.Ther. 271 390 PMID: 7965740

Kiriyama et al (1997) Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 122 217 PMID: 9313928

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关键词: Misoprostol, Misoprostol supplier, Cytoprotective, PGE1, EP1, EP2, EP3, EP4, Receptors, Prostanoid, prostaglandins, prostacyclins, eicosanoids, 2297, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Misoprostol, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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