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ML 402

Cat. No. 6888 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6888 has been discontinued.

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说明： Selective TREK channel activator
化学名： N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for ML 402

ML 402 is a selective TREK channel activator. Selectively activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with no significant effect at K2P4.1 channels (TRAAK).

化合物库 for ML 402

ML 402 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for ML 402

分子量 295.78
公式 C14H14ClNO2S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 298684-44-3
PubChem ID 592973
InChI Key RULQUKFOBAPKKR-UHFFFAOYSA-N
Smiles CC1=C(OCCNC(=O)C2=CC=CS2)C=CC(Cl)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for ML 402

参考文献是支持产品生物活性的出版物。

Lolicato et al (2017) K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature 547 364 PMID: 28693035

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关键词: ML 402, ML 402 supplier, ML402, k2p2.1, 10.1, channels, activators, activates, TREK-1, TREK-2, Two-P, potassium, Potassium, Channels, 6888, Tocris Bioscience

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