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说明： Potent NMDA antagonist, acts glycine site
化学名： 5,7-Dinitroquinoxaline-2,3-dione
生物活性 for MNQX
NMDA/glycine site antagonist, more potent than the structurally related CNQX. Also an AMPA/kainate antagonist, less potent than CNQX.
技术数据 for MNQX
| 分子量 | 252.14 |
| 储存 | Store at RT |
| CAS Number | 125910-83-0 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for MNQX
分析证书目前不在网上提供。
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参考文献 for MNQX
参考文献是支持产品生物活性的出版物。
Sheardown et al (1989) A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties. Eur.J.Pharmacol. 174 197 PMID: 2560979
Watkins et al (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS 11 25 PMID: 2155495
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关键词: MNQX, MNQX supplier, NMDA, Receptors, 0277, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:
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- Transcriptional Dysregulation
- Mitochondrial Dysfunction
- Nuclear-Cytoplasmic Transport Interference
- Excitotoxicity
- Stem Cells
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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.