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Submit ReviewMRS 2690
说明： Potent P2Y14 agonist
化学名： Diphosphoric acid 1-α-D-glucopyranosyl ester 2-[(4'-methylthio)uridin-5''-yl] ester disodium salt
纯度： ≥98% (HPLC)
生物活性 for MRS 2690
MRS 2690 is a potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
This product is typically reconstituted in water.
技术数据 for MRS 2690
| 分子量 | 626.33 |
| 公式 | C15H22N2Na2O16P2S |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| PubChem ID | 73755042 |
| InChI Key | TYVFMVSNSGMZPA-QBNUFUENSA-L |
| Smiles | [Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=S)[C@H](O)[C@@H](O)[C@@H]1O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for MRS 2690
参考文献 for MRS 2690
参考文献是支持产品生物活性的出版物。
Ko et al (2007) Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J.Med.Chem. 50 2030 PMID: 17407275
If you know of a relevant reference for MRS 2690, please let us know.
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关键词: MRS 2690, MRS 2690 supplier, Potent, P2Y14, agonists, Receptors, Purinergic, purinoceptors, MRS2690, 15039-58-4, P2Y, 2915, Tocris Bioscience
1 篇 MRS 2690 的引用文献
引用文献是使用了 Tocris 产品的出版物。 MRS 2690 的部分引用包括：
Gao et al (2013) The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells. Neuropsychopharmacology 9 31 PMID: 22825617
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MRS 2690 的评论
平均评分: 5 (Based on 1 Review.)
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P2Y14 agonist.
By
Anonymous on 09/20/2018
分析类型： Ex Vivo
种属： Mouse
P2Y14 activation.
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.