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MRS 2905

Cat. No. 5633 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Potent and selective P2Y14 receptor agonist
化学名： 2-Thiouridine-5'-O-(α, β-methylene)diphosphate trisodium salt
纯度： ≥98% (HPLC)
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引用文献
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生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for MRS 2905

MRS 2905 is a potent and selective P2Y14 receptor agonist (EC50 = 0.92 nM). Exhibits >2000-fold selectivity over P2Y6.

技术数据 for MRS 2905

分子量 484.2
公式 C10H13N2Na3O10P2S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 3033550-04-5
PubChem ID 121513874
InChI Key YLWNGINRXVXFAA-ZXSRDNBLSA-K
Smiles O[C@H]1[C@H](O)[C@H](N2C(NC(C=C2)=O)=S)O[C@@H]1COP(CP(O[Na])(O[Na])=O)(O[Na])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for MRS 2905

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 21.79 45

制备储备液 for MRS 2905

以下数据基于产品分子量 484.2。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.45 mM 4.59 mL 22.95 mL 45.89 mL
2.25 mM 0.92 mL 4.59 mL 9.18 mL
4.5 mM 0.46 mL 2.29 mL 4.59 mL
22.5 mM 0.09 mL 0.46 mL 0.92 mL

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产品说明书 for MRS 2905

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for MRS 2905

参考文献是支持产品生物活性的出版物。

Das et al (2010) Human P2Y14 receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups J.Med.Chem. 53 471 PMID: 19902968

Lazarowski et al (2015) UDP-sugars as extracellular signaling molecules: cellular and physiologic consequences of P2Y14 receptor activation. Mol.Pharmacol. 88 151 PMID: 25829059

If you know of a relevant reference for MRS 2905, please let us know.

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关键词: MRS 2905, MRS 2905 supplier, MRS2905, Potent, selective, P2Y14, receptors, agonists, agonism, Purinergic, P2Y, Receptors, 5633, Tocris Bioscience

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P2X and P2Y Receptors Scientific Review

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