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Submit ReviewMRS 2957 triethylammonium salt
说明： Potent and selective P2Y6 agonist
化学名： P1-[5'(N4-Methoxycytidyl)]-P3-(5'-uridyl)-triphosphate tri(triethylammonium) salt
纯度： ≥99% (HPLC)
生物活性 for MRS 2957 triethylammonium salt
MRS 2957 triethylammonium salt is a potent P2Y6 agonist (EC50 = 12 nM). Displays 14- and 66-fold selectivity against P2Y2 and P2Y4 receptors respectively.
技术数据 for MRS 2957 triethylammonium salt
| 分子量 | 1042.94 |
| 公式 | C19H28N5O20P3.3(C2H5)3N |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| PubChem ID | 90488923 |
| InChI Key | UCQYWKBGVXRIQK-BJFMRLMLSA-N |
| Smiles | O[C@@H]1[C@@H](N2C(NC(C=C2)=O)=O)O[C@@H](COP(OP(OP(OC[C@H]3O[C@@H](N4C(NC(C=C4)=NOC)=O)[C@H](O)[C@@H]3O)([O-])=O)([O-])=O)([O-])=O)[C@@H]1O.CC[NH+](CC)CC.CC[NH+](CC)CC.CC[NH+](CC)CC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for MRS 2957 triethylammonium salt
参考文献 for MRS 2957 triethylammonium salt
参考文献是支持产品生物活性的出版物。
Maruoka et al (2010) Pyrimidine ribonucleotides with enhanced selectivity as P2Y6 receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate γ-ester modifications. J.Med.Chem. 53 4488 PMID: 20446735
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关键词: MRS 2957 triethylammonium salt, MRS 2957 triethylammonium salt supplier, MRS2957, triethylammonium, salt, potent, selective, purinergics, purines, purinoceptors, p2y6, agonists, 1228271-30-4, Purinergic, P2Y, Receptors, 4260, Tocris Bioscience
1 篇 MRS 2957 triethylammonium salt 的引用文献
引用文献是使用了 Tocris 产品的出版物。 MRS 2957 triethylammonium salt 的部分引用包括：
Balasubramanian et al (2014) Enhancement of glucose uptake in mouse skeletal muscle cells and adipocytes by P2Y6 receptor agonists. Nat Methods 9 e116203 PMID: 25549240
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
P2X and P2Y Receptors Scientific Review
Written by Kenneth Jacobson, this review provides an overview of the different subtypes and structures of the P2 receptor families, as well as the pharmacological probes used to study them; compounds available from Tocris are listed.