MRS 3777 hemioxalate

Name: MRS 3777 hemioxalate
Brand: Tocris Bioscience
SKU: 2403

Cat. No. 2403 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2403 has been discontinued.

View all Adenosine A<sub>3</sub> Receptors products.

说明： High affinity, selective A₃ antagonist

化学名： 2-Phenoxy-6-(cyclohexylamino)purine hemioxalate

纯度： ≥98% (HPLC)

说明书

引用文献 (1)

生物活性技术数据说明书参考文献

生物活性 for MRS 3777 hemioxalate

High affinity adenosine A₃ receptor antagonist (K_i = 47 nM) that displays > 200-fold selectivity versus A₁, A_2A and A_2B receptors.

技术数据 for MRS 3777 hemioxalate

分子量	354.39
公式	C₁₇H₁₉N₅O.½C₂H₂O₄
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	1186195-57-2
PubChem ID	56972200
InChI Key	ICOKMZZMQHZKGX-UHFFFAOYSA-N
Smiles	OC(=O)C(O)=O.C1CCC(CC1)NC1=C2N=CNC2=NC(OC2=CC=CC=C2)=N1.C1CCC(CC1)NC1=C2N=CNC2=NC(OC2=CC=CC=C2)=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for MRS 3777 hemioxalate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for MRS 3777 hemioxalate

参考文献是支持产品生物活性的出版物。

Perreira et al (2005) "Reversine" and its 2-substituted adenine derivatives as potent and selective A₃ adenosine receptor antagonists. J.Med.Chem. 48 4910 PMID: 16033270

Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247 PMID: 16518376

Moro et al (2006) Progress in the pursuit of therapeutic adenosine receptor antagonists. Med.Res.Rev. 26 131 PMID: 16380972

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关键词: MRS 3777 hemioxalate, MRS 3777 hemioxalate supplier, High, affinity, selective, A3, antagonists, Receptors, adenosines, MRS3777, hemioxalate, Adenosine, 2403, Tocris Bioscience

1 篇 MRS 3777 hemioxalate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 MRS 3777 hemioxalate 的部分引用包括：

Schneider et al (2015) Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Nature 14 201 PMID: 26597723