Adenosine A3 Receptors
The adenosine A3 receptor is a member of the adenosine receptor group of G-protein-coupled receptors that also includes A1, A2A and A2B. They display high expression levels in the testes and mast cells of rats, with low expression levels in the thyroid, liver, kidney and heart.
Adenosine A3 Receptor Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 1104 | 2-Cl-IB-MECA |
| Highly selective A3 agonist | |
| 1579 | HEMADO |
| High affinity selective A3 agonist | |
| 1066 | IB-MECA |
| A3 selective agonist | |
Adenosine A3 Receptor Antagonists |
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| Cat. No. | Product Name / Activity |
| 7628 | DPTN |
| Potent and selective A3 adenosine receptor antagonist | |
| 1217 | MRS 1220 |
| Highly potent and selective hA3 antagonist | |
| 1385 | MRS 1334 |
| Potent, highly selective hA3 antagonist | |
| 2010 | PSB 10 hydrochloride |
| Potent, highly selective hA3 receptor antagonist/inverse agonist | |
Other |
|
| Cat. No. | Product Name / Activity |
| 7954 | CELT-327 |
| Potent and selective hA2B/A3 adenosine receptor fluorescent antagonist | |
The adenosine A3 receptor is a member of the adenosine receptor group of G-protein-coupled receptors that also includes A1, A2A and A2B. They display high expression levels in the testes and mast cells of rats, with low expression levels in the thyroid, liver, kidney, heart, intestine and most brain areas. Adenosine A3 receptors play a role in mast cell degranulation, coronary vasodilation and protection from reperfusion. The human A3 receptor gene is localized on chromosome 1 (1p21-p13).