N⁶-Cyclopentyladenosine

Cat. No. 1702 12 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Potent and selective A₁ agonist

别名： CPA

化学名： N-Cyclopentyladenosine

纯度： ≥99% (HPLC)

引用文献 (12)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for N⁶-Cyclopentyladenosine

N⁶-Cyclopentyladenosine is a potent and selective adenosine A₁ receptor agonist (K_i values are 2.3, 790 and 43 nM for human A₁, A_2A and A₃ receptors respectively; EC₅₀ = 18600 nM for hA_2B). Centrally active following systemic administration in vivo.

技术数据 for N⁶-Cyclopentyladenosine

分子量	335.36
公式	C₁₅H₂₁N₅O₄
储存	Desiccate at +4°C
纯度	≥99% (HPLC)
CAS Number	41552-82-3
PubChem ID	657378
InChI Key	SQMWSBKSHWARHU-SDBHATRESA-N
Smiles	O[C@@H]1[C@@H](CO)O[C@@H](N(C=N4)C2=C4C(NC3CCCC3)=NC=N2)[C@@H]1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for N⁶-Cyclopentyladenosine

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	1eq. HCl	33.54	100

制备储备液 for N⁶-Cyclopentyladenosine

以下数据基于产品分子量 335.36。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.98 mL	14.91 mL	29.82 mL
5 mM	0.6 mL	2.98 mL	5.96 mL
10 mM	0.3 mL	1.49 mL	2.98 mL
50 mM	0.06 mL	0.3 mL	0.6 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for N⁶-Cyclopentyladenosine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for N⁶-Cyclopentyladenosine

参考文献是支持产品生物活性的出版物。

Coffin and Spealman (1987) Behavioral and cardiovascular effects of analogs of adenosine in Cynomolgus monkeys. J.Pharmacol.Exp.Ther. 241 76 PMID: 3572798

Klotz (2000) Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch.Pharmacol. 362 382 PMID: 11111832

Van der Graaf et al (1997) Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N⁶-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A₁ receptors. J.Pharmacol.Exp.Ther. 283 809 PMID: 9353402

If you know of a relevant reference for N⁶-Cyclopentyladenosine, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Adenosine A₁ Receptor Agonists

关键词: N6-Cyclopentyladenosine, N6-Cyclopentyladenosine supplier, Potent, selective, A1, agonists, Receptors, adenosines, CPA, Adenosine, 1702, Tocris Bioscience