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Submit ReviewNalmefene hydrochloride
说明： Opioid receptor antagonist
化学名： (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Nalmefene hydrochloride
Nalmefene hydrochloride is an opioid receptor antagonist; displays a longer half life than Naloxone. Exhibits neuroprotective effects after traumatic brain injury in the rat.
化合物库 for Nalmefene hydrochloride
Nalmefene hydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
技术数据 for Nalmefene hydrochloride
| 分子量 | 375.89 |
| 公式 | C21H25NO3.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 58895-64-0 |
| PubChem ID | 5388881 |
| InChI Key | GYWMRGWFQPSQLK-OPHZJPRHSA-N |
| Smiles | C=C3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(CC6CC6)CC4)[C@@](O)2CC3.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Nalmefene hydrochloride
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 37.59 | 100 | |
| DMSO | 37.59 | 100 |
制备储备液 for Nalmefene hydrochloride
以下数据基于产品分子量 375.89。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.66 mL | 13.3 mL | 26.6 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.32 mL |
| 10 mM | 0.27 mL | 1.33 mL | 2.66 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.53 mL |
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产品说明书 for Nalmefene hydrochloride
参考文献 for Nalmefene hydrochloride
参考文献是支持产品生物活性的出版物。
Vink et al (1990) Opiate antagonist nalmefene improves intracellular free Mg2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats. J.Neurosci. 10 3524 PMID: 2230942
If you know of a relevant reference for Nalmefene hydrochloride, please let us know.
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关键词: Nalmefene hydrochloride, Nalmefene hydrochloride supplier, opioid, receptor, antagonist, antagonists, Miscellaneous/Non-selective, Opioids, 4085, Tocris Bioscience
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