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Submit ReviewNaproxen sodium is a non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
分子量 | 252.24 |
公式 | C14H13NaO3 |
储存 | Desiccate at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 26159-34-2 |
PubChem ID | 23681059 |
InChI Key | CDBRNDSHEYLDJV-FVGYRXGTSA-M |
Smiles | [Na+].COC1=CC=C2C=C(C=CC2=C1)[C@H](C)C([O-])=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Sutton (1996) Naproxen sodium. J.Am.Pharm.Assoc. (Wash) NS36 633 PMID: 8952250
Dhir et al (2006) Protective effect of naproxen (non-selective COX-inhibitor) or rofe. (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. Eur.J.Pharmacol. 535 192 PMID: 16522321
Kumar et al (2006) Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. Eur.J.Pharmacol. 551 58 PMID: 17027965
关键词: Naproxen sodium, Naproxen sodium supplier, Cyclooxygenase, inhibitors, inhibits, COX, Oxygenases, Oxidases, oxidative, stress, 2655, Tocris Bioscience
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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.