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Submit ReviewNIDA 41020
说明： High affinity CB1 antagonist
化学名： N-(Piperidin-1-yl)-5-(4-methoxyphenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
纯度： ≥99% (HPLC)
生物活性 for NIDA 41020
High affinity CB1 receptor antagonist (Ki = 4.1 nM). Exhibits significantly reduced lipophilicity compared to other CB1 antagonists.
技术数据 for NIDA 41020
| 分子量 | 459.37 |
| 公式 | C23H24Cl2N4O2 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 502486-89-7 |
| PubChem ID | 11037861 |
| InChI Key | KWDBQJRWPWTGPF-UHFFFAOYSA-N |
| Smiles | O=C(NN3CCCCC3)C1=NN(C2=CC=C(Cl)C=C2Cl)C(C4=CC=C(OC)C=C4)=C1C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for NIDA 41020
参考文献 for NIDA 41020
参考文献是支持产品生物活性的出版物。
Katoch-Rouse et al (2003) Synthesis, structure-activity relationship and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity. J.Med.Chem. 46 642 PMID: 12570386
Miller et al (2007) Analogs of SR-141716A (Rimonabant) alter d-amphetamine-evoked [3H] DA overflow from preloaded striatal slices and amphetamine-induced hyperactivity. Life Sci. 81 63 PMID: 17532007
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关键词: NIDA 41020, NIDA 41020 supplier, NIDA41020, cannabinoid, receptors, antagonists, CB1, selective, Receptors, 3921, Tocris Bioscience
1 篇 NIDA 41020 的引用文献
引用文献是使用了 Tocris 产品的出版物。 NIDA 41020 的部分引用包括：
Buznikov et al (2010) A putative 'pre-nervous' endocannabinoid system in early echinoderm development. Dev Neurosci 32 1 PMID: 19907129
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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