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Norleual

Cat. No. 5369 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5369 has been discontinued.

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说明： Highly potent HGF/c-MET inhibitor; also AT4 antagonist
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Norleual

Norleual is an angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic.

技术数据 for Norleual

分子量 774.95
公式 C41H58N8O7
序列 XYLHPF

(Modifications: X = Nle, Leu-3-His-4 peptide bond replaced with CH2NH)

储存 Store at -20°C
CAS Number 334994-34-2
PubChem ID 91691127
InChI Key LOHDEFSMLITXTG-RZAPKHMUSA-N
Smiles [H]N(C(CC1=CC=C(O)C=C1)C(=O)N[C@H](CN[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)CC(C)C)C(=O)[C@@H](N)CCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Norleual

参考文献是支持产品生物活性的出版物。

Yamamoto et al (2010) The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor. J.Pharmacol.Exp.Ther. 333 161 PMID: 20086056

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关键词: Norleual, Norleual supplier, potent, HGF, c-MET, hepatocyte, growth, factors, HGF/c-MET, inhibits, inhibitors, antiangiogenic, angiogenesis, tyrosine, kinases, angiotensin, IV, analog, receptors, AT4, antagonists, MET, Receptors, 5369, Tocris Bioscience

1 篇 Norleual 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Norleual 的部分引用包括：

El-Habta et al (2018) The adipose tissue stromal vascular fraction secretome enhances the proliferation but inhibits the differentiation of myoblasts. Stem Cell Res Ther 9 352 PMID: 30572954

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