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Submit ReviewNPEC-caged-dopamine
说明： Caged dopamine
化学名： (N)-1-(2-Nitrophenyl)ethylcarboxy-3,4-dihydroxyphenethylamine
纯度： ≥99% (HPLC)
生物活性 for NPEC-caged-dopamine
NPEC-caged-dopamine is a NPEC ((N)-1-(2-nitrophenyl)ethyl) caged version of dopamine (Cat. No 3548); releases dopamine leading to D1 receptor activation upon UV light illumination (360 nm). Induces PKA activation and c-Fos expression in cortical and striatal neurons, with striatal neurons demonstrating a significantly greater detection and sensitivity to sub-second dopamine signals as compared to cortical neurons.
技术数据 for NPEC-caged-dopamine
| 分子量 | 346.33 |
| 公式 | C17H18N2O6 |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 1257326-23-0 |
| PubChem ID | 90488901 |
| InChI Key | PDNNZLULXSQJGZ-UHFFFAOYSA-N |
| Smiles | CC(OC(NCCC2=CC=C(O)C(O)=C2)=O)C1=C([N+]([O-])=O)C=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for NPEC-caged-dopamine
参考文献 for NPEC-caged-dopamine
参考文献是支持产品生物活性的出版物。
Castro et al (2013) Striatal neurones have a specific ability to respond to phasic DA release. J.Physiol. 591 3197 PMID: 23551948
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关键词: NPEC-caged-dopamine, NPEC-caged-dopamine supplier, caged, dopamine, compounds, neurotransmitters, D, receptors, dopaminergic, Caged, Dopamine, Compounds, D1, and, D5, Receptors, Non-selective, 3992, Tocris Bioscience
2 篇 NPEC-caged-dopamine 的引用文献
引用文献是使用了 Tocris 产品的出版物。 NPEC-caged-dopamine 的部分引用包括：
Yapo et al (2017) Detection of phasic DA by D1 and D2 striatal medium spiny neurons. J.Physiol. 595 7451 PMID: 28782235
Castro et al (2013) Striatal neurones have a specific ability to respond to phasic DA release. J.Physiol. 591 3197 PMID: 23551948
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.