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NVP CXCR2 20

Cat. No. 5660 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5660 has been discontinued.

View all Chemokine CXC Receptors products.
说明： Potent and selective CXCR2 antagonist
化学名： 4-Cyclopropyl-2-[[(2,3-difluorophenyl)methyl]thio]-1,6-dihydro-6-oxo5-pyrimidinecarbonitrile
纯度： ≥98% (HPLC)
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for NVP CXCR2 20

Potent and selective CXCR2 antagonist (IC50 = 40 nM). Exhibits selectivity for CXCR2 over a panel of 49 other GPCRs. Orally bioavailable.

化合物库 for NVP CXCR2 20

NVP CXCR2 20 is also offered as part of the Tocriscreen Antiviral Library. 了解 Tocris 化合物库的更多信息。

技术数据 for NVP CXCR2 20

分子量 319.33
公式 C15H11F2N3OS
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 1029521-30-9
PubChem ID 24955240
InChI Key PHHZYKZFEBRXAL-UHFFFAOYSA-N
Smiles OC1=C(C#N)C(C2CC2)=NC(SCC3=CC=CC(F)=C3F)=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for NVP CXCR2 20

参考文献是支持产品生物活性的出版物。

Porter et al (2014) The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists. Bioorg.Med.Chem.Lett. 24 3285 PMID: 24974342

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关键词: NVP CXCR2 20, NVP CXCR2 20 supplier, NVPCXCR220, chemokine, cxc, receptors, antagonists, antagonism, orally, bioavailable, potent, selective, Chemokine, CXC, Receptors, 5660, Tocris Bioscience

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