O4I2

Cat. No. 5664 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Oct3/4 inducer; induces expression of pluripotent-associated genes

化学名： Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (4)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for O4I2

O4I2 is an Oct3/4 inducer; promotes Oct3/4 expression and stabilizes the Oct3/4 protein in HEK293 cells. Induces expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1. Induces 15-fold increase in Oct3/4 expression in human primary fibroblasts.

化合物库 for O4I2

O4I2 is also offered as part of the Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for O4I2

分子量	282.75
公式	C₁₂H₁₁ClN₂O₂S
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	165682-93-9
PubChem ID	53428670
InChI Key	ULUBAPWNHROTEU-UHFFFAOYSA-N
Smiles	ClC(C=C2)=CC=C2NC1=NC(C(OCC)=O)=CS1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for O4I2

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	28.27	100
	ethanol	14.14	50

制备储备液 for O4I2

以下数据基于产品分子量 282.75。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.54 mL	17.68 mL	35.37 mL
5 mM	0.71 mL	3.54 mL	7.07 mL
10 mM	0.35 mL	1.77 mL	3.54 mL
50 mM	0.07 mL	0.35 mL	0.71 mL

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产品说明书 for O4I2

分析证书/产品说明书

化学品安全技术说明书

参考文献 for O4I2

参考文献是支持产品生物活性的出版物。

Cheng et al (2015) Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and derivatives are potent inducers of Oct3/4. J.Med.Chem. 58 5742 PMID: 26143659

If you know of a relevant reference for O4I2, please let us know.

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关键词: O4I2, O4I2 supplier, octamer, binding, transcription, factors, oct4, inducing, compound, 2, Oct3/4, inducers, pluripotent, stem, cells, induction, Stem, Cell, Reprogramming, Other, Transcription, Factors, 5664, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

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