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Ochratoxin A

Cat. No. 1291 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1291 has been discontinued.

说明： Stimulates SERCA-ATP-dependent Ca2+ pump activity
化学名： N-[[(3R)-5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Ochratoxin A

Ochratoxin A is a mycotoxin that increases activity of the endoplasmic reticulum ATP-dependent calcium pump. Induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations. Stimulates lipid peroxidation.

技术数据 for Ochratoxin A

分子量 403.82
公式 C20H18ClNO6
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 303-47-9
PubChem ID 442530
InChI Key RWQKHEORZBHNRI-BMIGLBTASA-N
Smiles OC1=C(C(N[C@H]([C@@](O)=O)CC3=CC=CC=C3)=O)C=C(Cl)C2=C1C(O[C@H](C)C2)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Ochratoxin A

分析证书/产品说明书
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参考文献 for Ochratoxin A

参考文献是支持产品生物活性的出版物。

Chong and Rahimtula (1992) Alterations in ATP-dependent calcium uptake by rat renal cortex microsomes following ochratoxin A administration in vitro. Biochem.Pharmacol. 44 1401 PMID: 1417961

Dirheimer and Creppy (1991) Mechanism of action of ochratoxin A. IARC Sci.Publ. 115 171 PMID: 1820332

Gekle et al (2000) Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations. J.Pharmacol.Exp.Ther. 293 837 PMID: 10869383

Omar et al (1991) Role of cytochrome-P-450 in ochratoxin-A stimulated lipid-peroxidation. J.Biochem.Toxicol. 6 203 PMID: 1770504

Merck Index 12 6836

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关键词: Ochratoxin A, Ochratoxin A supplier, Stimulates, stimulators, SERCA-ATPase, Ca2+, pump, activity, modulators, Ca2+-ATPase, Calcium-ATPase, Ion, Transporters, Pumps, OchratoxinA, 1291, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Ochratoxin A, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

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