Olmesartan medoxomil

Name: Olmesartan medoxomil
Brand: Tocris Bioscience
SKU: 4620

Cat. No. 4620 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4620 has been discontinued.

View all Angiotensin AT<sub>1</sub> Receptors products.

说明： Selective non-peptide AT₁ antagonist; prodrug of Olmesartan

化学名： 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-carboxylic acid-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Olmesartan medoxomil

Prodrug metabolised in vivo to Olmesartan (Cat. No. 4616), a selective non-peptide angiotensin II type I receptor (AT₁) antagonist. Selectively inhibits angiotensin II binding to AT₁ receptors in bovine adrenal cortical membranes (IC₅₀ = 7.7 nM), with no effect on AT₂ receptors.

化合物库 for Olmesartan medoxomil

Olmesartan medoxomil is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Olmesartan medoxomil

分子量	558.59
公式	C₂₉H₃₀N₆O₆
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	144689-63-4
PubChem ID	130881
InChI Key	UQGKUQLKSCSZGY-UHFFFAOYSA-N
Smiles	CCCC1=NC(C(C)(C)O)=C(C(OCC(O5)=C(C)OC5=O)=O)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Olmesartan medoxomil

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Olmesartan medoxomil

参考文献是支持产品生物活性的出版物。

Kim et al (1997) Effects of angiotensin AT₁ receptor antagonist on volume overload-induced cardiac gene expression in rats. Hypertens.Res. 20 133 PMID: 9220278

Mizuno et al (1995) Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist. Eur.J.Pharmacol. 285 181 PMID: 8566137

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关键词: Olmesartan medoxomil, Olmesartan medoxomil supplier, CS866, antagonists, RNH-6270, AT1, receptors, angiotensin, II, type, I, receptor, Angiotensin, Receptors, 4620, Tocris Bioscience

篇 Olmesartan medoxomil 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Olmesartan medoxomil 的引用文献。