主页 / 药理学 / Ion Channels / Sodium Channels / Voltage-gated Sodium (NaV) Channels / Voltage-gated Sodium (NaV) Channel Blockers / Oxcarbazepine

Oxcarbazepine

Cat. No. 3864 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Anticonvulsant; inhibits Na+ channel activity
化学名： 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Oxcarbazepine

Oxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.

技术数据 for Oxcarbazepine

分子量 252.27
公式 C15H12N2O2
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 28721-07-5
PubChem ID 34312
InChI Key CTRLABGOLIVAIY-UHFFFAOYSA-N
Smiles NC(N(C(C=CC=C3)=C3C2)C1=CC=CC=C1C2=O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Oxcarbazepine

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 12.61 50

制备储备液 for Oxcarbazepine

以下数据基于产品分子量 252.27。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 7.93 mL 39.64 mL 79.28 mL
2.5 mM 1.59 mL 7.93 mL 15.86 mL
5 mM 0.79 mL 3.96 mL 7.93 mL
25 mM 0.16 mL 0.79 mL 1.59 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for Oxcarbazepine

参考文献是支持产品生物活性的出版物。

Schmutz et al (1994) Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action. Epilepsia 35 S47 PMID: 8039471

Ambrosio et al (2002) Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochem.Res. 27 121 PMID: 11926264

Zheng et al (2009) Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures. Epilepsia 50 83 PMID: 18717705

If you know of a relevant reference for Oxcarbazepine, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Voltage-gated Sodium (NaV) Channel Blockers

关键词: Oxcarbazepine, Oxcarbazepine supplier, antiepileptics, anticonvulsants, anticonvulsives, sodium, channels, voltage-gated, Na+, voltage-dependent, inhibitors, inhibits, NaV, Voltage-gated, Sodium, Channels, 3864, Tocris Bioscience

篇 Oxcarbazepine 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Oxcarbazepine 的引用文献。 您是否知道使用了 Tocris Oxcarbazepine 的优秀论文？ 请告知我们.

Oxcarbazepine 的评论

平均评分: 5 (Based on 1 Review.)

5 星
100%
4 星
0%
3 星
0%
2 星
0%
1 星
0%

Have you used Oxcarbazepine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Suppression of seizure-like events.
By Luca Zangrandi on 08/13/2021
分析类型： In Vivo
种属： Mouse

Systemic in-vivo administration

review image